As global populations continue to increase, agricultural productivity will be challenged to keep pace without overtaxing important environmental resources. A dynamic and integrated approach will be required to solve global food insecurity and position agriculture on a trajectory toward sustainability. Genetically modified (GM) crops enhanced through modern biotechnology represent an important set of tools that can promote sustainable agriculture and improve food security.

Inefficiencies and imprecise input control in agriculture have caused devastating consequences to ecosystems. Urban controlled environment agriculture (CEA) is a proposed approach to mitigate the impacts of cultivation, but precise control of inputs (i.e., nutrient, water, etc.) is limited by the ability to monitor dynamic conditions. Current mechanistic and physiological plant growth models (MPMs) have not yet been unified and have uncovered knowledge gaps of the complex interplay among control variables.