Agricultural knowledge and innovation system (AKIS) has a strong potential to enhance economic performance of farming and contribute to agricultural sustainability, as it may increase synergies and complementarity among actors. This paper is aimed to develop a proposed framework to strengthen AKIS in the study area based on the results of this study. This paper explores perception and views about strengthening AKIS in Dakhalia governorate of Egypt by applying a multi-actor approach. Quantitative and qualitative data were collected through face-to-face interviews and focus group discussion.