This paper analyzes how the Papa Andina Partnership Program, based at the International Potato Center, functions as an innovation broker in the Andean potato sector. As a regional initiative, Papa Andina operates as a second-level innovation broker, backstopping national partners who facilitate local innovation processes in their respective countries. Papa Andina works to strengthen local innovation capacity and to foster innovations in innovation the development of more effective ways of bringing stakeholders together to produce innovations that benefit small-scale farmers.