Parasitic weeds such as Striga spp and Rhamphicarpa fistulosa in smallholder rice production systems form an increasing problem for food and income security in sub-Saharan Africa. In this paper we implement the Rapid Appraisal of Agricultural Innovation Systems (RAAIS) as a diagnostic tool to identify specific and generic entry points for innovations to address parasitic weeds in rain-fed rice production in Tanzania. Data were gathered across three study sites in Tanzania where parasitic weeds are eminent (Kyela, Songea Rural and Morogoro Rural districts).