Innovation systems and science and technology (S&T) projects supported by the World Bank have taken on many forms in the past several years. The Bank's involvement in industrial technology projects started in the 1970s, with Israel and Spain numbering among the first countries to receive support in the form of industrial technology development. This paper reviews the lessons learned in S&T projects that have been supported by the Bank, with an emphasis on the examples of the past decade (1989-2003).