Brazilian agriculture is facing another expansion cycle to the Cerrado region, more specific in the Northeast. The first agriculture expansion cycle to the Midwest was in seventies encouraged and developed by Brazilian Government with farmers from southern and southeast Brazil, which were traditional small farmers with some experience, low budget and a remarkable determination. All of these efforts after 20 years resulted in an outstanding development of a part of the country with economy based on agribusiness (soybean, corn, cotton, livestock, poultry, swine, etc.).

Providing food and other products to a growing human population while safeguarding natural ecosystems and the provision of their services is a significant scientific, social and political challenge. With food demand likely to double over the next four decades, anthropization is already driving climate change and is the principal force behind species extinction, among other environmental impacts. The sustainable intensification of production on current agricultural lands has been suggested as a key solution to the competition for land between agriculture and natural ecosystems.

In the Amazon, slash and burn is the most common technique used by American-Indians, small farmers and even big ranches to transform forests into rural landscapes. The basis of food subsistence for diverse populations (rice, corn and bean), slash and burn is also a must for the plantation of cocoa, coffee, palms and pastures. The Amazonian rural landscape is currently dominated by pastures, occupying around 80 % of the deforested surface.

Traditional shifting cultivation in the Amazon region has caused negative environmental and social effects due to the use of fire. This type of agriculture has been criticized because it results in emission of large amounts of carbon into the atmosphere and a loss of soil productive potential.

One of the most important challenges for the researchers in the 21st Century is related to global heating and climate change that can have as consequence the intensification of natural hazards. Another problem of changes in the Earth's climate is its impact in the agriculture production. In this scenario, application of statistical models as well as development of new methods become very important to aid in the analyses of climate from ground-based stations and outputs of forecasting models. Additionally, remote sensing images have been used to improve the monitoring of crop yields.

There is increasing evidence that public organizations dedicated exclusively to research and development (R&D) in agribusiness need systematic management tools to incorporate the uncertainties and complexities of technological and nontechnological factors of external environments in its long-term strategic plans. The major issues are: What will be the agribusiness science and technology (S&T) needs be in the future? How to prepare in order to meet these needs?

Brazilian agriculture is a success story. The country that until the 1960s systematically received food donations from abroad. and up to the 1980s was still a large food importer, had its agriculture profoundly changed. The traditional agriculture that prevailed in Brazil until the 1970s was progressively transformed in the following decades into a modern and highly competitive agriculture based on science.

Transgenic maize was approved in Brazil in 2008/2009. In 2012, it occupied 73% of the country maize growing area. This high adoption rate confirms studies indicating that technology use has been the major driving force in Brazilian agriculture. Maize seed market in the world has been a concentrated sector. Although, when this sector is associated with transgenesis, this concentration increases sharply. In one side, there is the idea that companies can benefit from gains of scale and complementarities to maximize their efficiency in research and development (R&D).

Family farms are by far the most numerous component of the agricultural sector in the Brazilian Amazon. However socially vital for the development of the region, these small landholdings' agricultural and cattle ranching activities frequently overdraw and degrade natural resources, threatening important ecosystem services. Predominant agricultural practices have been marked by shifting cultivation, with intense use of fire and low productivity, causing high rate of destruction of natural forests.

International partnership to carry out collaborative research and development programs has been implemented for a long time. However, with globalization, the economic, social, political and cultural diversity of interacting partners reached levels where this variety of collaborators often has shown some weaknesses in issues like governance. Strong and sound partnerships must be manageable in order to ensure the achievement of the set objectives.