This paper is based on the 8th GLOBELICS International Conference: Making Innovation Work for Society (1 - 3 November 2010, University of Malaya, Kuala Lumpur, Malaysia). The paper presents three projects of the Research Into Use Program, located in South asia, which are applying three agriculture value chain development oriented knowledge for wider use. Practical aspects of the process and roles played by different types of ageincies in the innovation are discussed.